“Researchers have known since the 1960s that your body metabolizes different types of carbohydrates, like glucose and fructose, in different ways, causing very different hormonal and physiological responses that absolutely may influence fat accumulation and metabolism. Unlike glucose, which can be used by virtually every cell in your body, fructose can only be metabolized by your liver, because your liver is the only organ that has the transporter for it.
Since all fructose gets shuttled to your liver, it ends up taxing your liver in the same way alcohol and other toxins do, particularly if you consume excess amounts of it. In fact...fructose is a chronic, dose-dependent liver toxin. And just like alcohol, fructose is metabolized directly into fat — not cellular energy, like glucose.”